Enables prostaglandin-D synthase activity and retinoid binding activity. Involved in cyclooxygenase pathway; gene expression; and regulation of circadian sleep/wake cycle, sleep. Acts upstream of or within negative regulation of male germ cell proliferation. Located in extracellular region. Is expre
ssed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to human PTGDS (prostaglandin D2 synthase). [provided by Alliance of Genome Resources, Jul 2025]
Enables prostaglandin-D synthase activity. Acts upstream of or within several processes, including negative regulation of male germ cell proliferation; prostaglandin metabolic process; and response to nematode. Predicted to be located in cytosol and nucleoplasm. Is expressed in several structures, i
ncluding alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human HPGDS (hematopoietic prostaglandin D synthase). [provided by Alliance of Genome Resources, Apr 2025]