Involved in several processes, including negative regulation of cell-cell adhesion; regulation of microvillus assembly; and regulation of synapse assembly. Acts upstream of or within leukocyte migration. Located in apical plasma membrane and microvillus membrane. Is active in glutamatergic synapse a
nd presynaptic membrane. Is expressed in several structures, including genitourinary system; integumental system; intraembryonic coelom; nervous system; and sensory organ. Orthologous to human PODXL (podocalyxin like). [provided by Alliance of Genome Resources, Jul 2025]
Predicted to be involved in leukocyte tethering or rolling. Predicted to be located in plasma membrane. Is expressed in genitourinary system; gut; nervous system; respiratory tract; and sensory organ. Orthologous to human PODXL2 (podocalyxin like 2). [provided b