Enables identical protein binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in nuclear envelope; nucleoplasm; and plasma membrane. Predicted to be part of nuclear pore central transport channel and nuclear pore nuclear basket. Is ex
pressed in cerebellum. Used to study intestinal pseudo-obstruction. Orthologous to human NUP35 (nucleoporin 35). [provided by Alliance of Genome Resources, Jul 2025]
Enables SUMO transferase activity and kinase activator activity. Involved in nuclear export. Acts upstream of or within intracellular glucose homeostasis and regulation of gluconeogenesis. Predicted to be located in annulate lamellae; cytoplasmic periphery of the nuclear pore complex; and nucleus. P
redicted to be part of SUMO ligase complex; nuclear pore cytoplasmic filaments; and nuclear pore nuclear basket. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; eye; genitourinary system; hemolymphoid system; and nervous system. Human ortholog(s) of this gene implicated in brain disease and inflammatory myofibroblastic tumor. Orthologous to human RANBP2 (RAN binding protein 2). [provided by Alliance of Genome Resources, Apr 2025]