Nelf Gene Search Result

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5 records found for search term Nelf

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1621569	Nelfe	negative elongation factor complex member E, Rdbp	Enables chromatin binding activity. Involved in negative regulation of transcription elongation by RNA polymerase II. Is active in chromatin. Is expressed in brain and early conceptus. Orthologous to human NELFE (negative elongation factor complex member E). [pr ... (more) ovided by Alliance of Genome Resources, Jul 2025]	17	35069367	35075348	Mouse	125	symbol , PhenoGen , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
733598	Nsmf	NMDA receptor synaptonuclear signaling and neuronal migration factor	Predicted to enable calcium-dependent protein binding activity. Involved in cellular response to gonadotropin stimulus. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; liver; lung; and sensory organ. Human ortholog(s) of t ... (more) his gene implicated in hypogonadotropic hypogonadism 7 with or without anosmia and hypogonadotropic hypogonadism 9 with or without anosmia. Orthologous to human NSMF (NMDA receptor synaptonuclear signaling and neuronal migration factor). [provided by Alliance of Genome Resources, Jul 2025]	2	24944370	24952893	Mouse	190	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1313652	Nelfa	negative elongation factor complex member A, Whsc2	Enables chromatin binding activity. Acts upstream of or within negative regulation of transcription elongation by RNA polymerase II. Located in nucleus. Is expressed in several structures, including blastocyst; early embryo; genitourinary system; liver; and spleen. Orthologous to human NELF ... (more) font-weight:700;'>NELFA (negative elongation factor complex member A). [provided by Alliance of Genome Resources, Jul 2025]	5	34055263	34093615	Mouse	114	symbol , PhenoGen , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1317256	Nelfb	negative elongation factor complex member B	This gene encodes subunit B of a metazoan-specific, four-subunit protein complex that regulates promoter-proximal pausing of RNA polymerase II. RNA polymerase II pausing is thought to be important for coordination of gene transcription during embryonic development and stress responses. Consistently, ... (more) disruption of this gene in mouse causes inner cell mass deficiency and embryonic lethality. In addition, this gene is required for maintenance of mouse embryonic stem cells by preventing expression of developmental genes. In adult mice, conditional deletion of this gene results in cardiomyopathy and impaired response to cardiac stress. Multiple protein isoforms are encoded through the use of a non-AUG (CUG) initiation codon and an alternative downstream AUG initiation codon. In addition, alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]	2	25089724	25101501	Mouse	87	symbol , PhenoGen , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1623245	Nelfcd	negative elongation factor complex member C/D, Th1l	Predicted to enable RNA binding activity. Predicted to be involved in negative regulation of transcription elongation by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of NELF complex. Is expressed in several structures, including 1s ... (more) t branchial arch; early embryo; limb; main olfactory bulb; and maxillary process. Orthologous to human NELFCD (negative elongation factor complex member C/D). [provided by Alliance of Genome Resources, Jul 2025]	2	174257623	174269298	Mouse	77	symbol , PhenoGen , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]