| 1313281 | Mars1 | methionine-tRNA synthetase 1 | The encoded protein belongs to the class I family of tRNA synthetases, a class of enzymes that charge tRNAs with their cognate amino acids. The related human gene product is essential for the translation initiation of mRNAs. This gene has an overlapping 3' UTR tail-to-tail arrangement with an adjace nt gene on the opposite strand that encodes an inhibitor of the CCAAT/enhancer-binding protein's DNA binding activity. This arrangement, conserved in human and mouse, may be involved in mRNA stability and possible functional and regulatory interaction of these adjacent overlapping genes. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2010] | 10 | 127132090 | 127147655 | Mouse | 158 | symbol , ensembl_gene_symbol , PhenoGen , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1320352 | Sla2 | Src-like-adaptor 2 | Predicted to enable signaling adaptor activity. Acts upstream of or within T cell activation. Located in late endosome and plasma membrane. Is expressed in thymus primordium. Orthologous to human SLA2 (Src like adaptor 2). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 156716071 | 156729161 | Mouse | 89 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1553072 | Mars2 | methionine-tRNA synthetase 2 (mitochondrial) | Predicted to enable methionine-tRNA ligase activity. Predicted to be involved in methionyl-tRNA aminoacylation. Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Human ortholog(s) of t his gene implicated in combined oxidative phosphorylation deficiency 25 and spastic ataxia 3. Orthologous to human MARS2 (methionyl-tRNA synthetase 2, mitochondrial). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 55276336 | 55279217 | Mouse | 110 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1618338 | Camsap3 | calmodulin regulated spectrin-associated protein family, member 3 | Enables microtubule minus-end binding activity. Involved in several processes, including establishment of epithelial cell apical/basal polarity; establishment or maintenance of microtubule cytoskeleton polarity; and regulation of microtubule polymerization. Acts upstream of or within in utero embryo nic development. Located in axoneme; ciliary basal body; and motile cilium. Colocalizes with microtubule minus-end. Is expressed in brain and lung epithelium. Orthologous to human CAMSAP3 (calmodulin regulated spectrin associated protein family member 3). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 3637237 | 3659075 | Mouse | 186 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1558576 | Zfhx2 | zinc finger homeobox 2 | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of sensory perception of pain. Acts upstream of or within adult behavior. Located in nucleus. Is expres sed in several structures, including gut; male reproductive system; musculature; nervous system; and urinary system. Used to study Marsili syndrome. Human ortholog(s) of this gene implicated in Marsili syndrome. Orthologous to human ZFHX2 (zinc finger homeobox 2). [provided by Alliance of Genome Resources, Jul 2025] | 14 | 55297722 | 55329875 | Mouse | 92 | description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 69162 | Nfix | nuclear factor I/X | Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including learning or memory; nervous system development; and regulation of DNA-templated transcription. Acts upstream of or within several processes, including exit from mitosis; myeloid leukocyte differentiation; and nervous system development. Is active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Used to study Scheuermann's disease and Sotos syndrome 2. Human ortholog(s) of this gene implicated in Marshall-Smith syndrome and Sotos syndrome 2. Orthologous to human NFIX (nuclear factor I X). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 85431341 | 85527086 | Mouse | 355 | description | gene, protein-coding, VALIDATED [RefSeq] |