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Gene: Mars1 (methionine-tRNA synthetase 1) Mus musculus
Symbol: Mars1
Name: methionine-tRNA synthetase 1
RGD ID: 1313281
Description: Exhibits methionine-tRNA ligase activity. Involved in methionyl-tRNA aminoacylation. Localizes to aminoacyl-tRNA synthetase multienzyme complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2U. Orthologous to human MARS1 (methionyl-tRNA synthetase 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: M; Mars; Met; methionine tRNA ligase; methionine--tRNA ligase; methionine--tRNA ligase, cytoplasmic; methionine-tRNA synthetase; methionyl-tRNA synthetase, cytoplasmic; MetRS; MGC90747; MTRNS
Homo sapiens (human) : MARS1 (methionyl-tRNA synthetase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mars1 (methionyl-tRNA synthetase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mars1 (methionyl-tRNA synthetase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MARS1 (methionyl-tRNA synthetase 1)
Canis lupus familiaris (dog) : MARS1 (methionyl-tRNA synthetase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mars1 (methionyl-tRNA synthetase 1)
Sus scrofa (pig) : MARS1 (methionyl-tRNA synthetase 1)
Chlorocebus sabaeus (African green monkey) : MARS1 (methionyl-tRNA synthetase 1)
Heterocephalus glaber (naked mole-rat) : Mars1 (methionyl-tRNA synthetase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl10127,296,221 - 127,311,786 (-)EnsemblGRCm38mm10GRCm38
GRCm3810127,296,221 - 127,311,786 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710126,733,277 - 126,748,842 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610126,699,175 - 126,714,588 (-)NCBImm8
Celera10129,688,532 - 129,704,394 (-)NCBICelera
Cytogenetic Map10D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Mars1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313281
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.