leucine zipper-EF-hand containing transmembrane protein 1
Enables calcium:proton antiporter activity. Involved in calcium export from the mitochondrion; mitochondrial calcium ion homeostasis; and protein complex oligomerization. Located in mitochondrial inner membrane. Is expressed in brain; embryo; gonad; liver; and seminiferous cord. Orthologous to human
Enables molecular adaptor activity. Involved in mitochondrion organization and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including non-canonical NF-kappaB signal transduction; nucleobase-containing compound biosynthetic process; and toll-like re
ceptor 4 signaling pathway. Located in mitochondrial inner membrane. Is active in nucleus. Is expressed in several structures, including brain; cranial ganglion; dorsal root ganglion; and retina. Orthologous to human LETMD1 (LETM1 domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
leucine zipper-EF-hand containing transmembrane protein 2
Predicted to enable transmembrane transporter activity. Predicted to be involved in mitochondrial calcium ion transmembrane transport and mitochondrion organization. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Orthologous to human LETM2 (leucine