Leprot Gene Search Result

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3 records found for search term Leprot

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1553364	Leprot	leptin receptor overlapping transcript	Predicted to enable signaling receptor binding activity. Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway; negative regulation of protein localization to cell surface; and negative regulation of signal transduction. Predicted to be located in Gol ... (more) gi apparatus. Predicted to be active in endosome. Is expressed in central nervous system; heart valve; and retina nuclear layer. Orthologous to human LEPROT (leptin receptor overlapping transcript). [provided by Alliance of Genome Resources, Jul 2025]	4	101504922	101516561	Mouse	94	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
10865	Lepr	leptin receptor	Enables leptin receptor activity. Involved in several processes, including glucose homeostasis; leptin-mediated signaling pathway; and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including glial cell proliferation; glycogen metabolic process; and ... (more) negative regulation of gluconeogenesis. Predicted to be located in extracellular space. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and respiratory system. Used to study metabolic dysfunction-associated steatotic liver disease; obesity; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); liver disease (multiple); obesity; obstructive sleep apnea; and type 2 diabetes mellitus. Orthologous to human LEPR (leptin receptor). [provided by Alliance of Genome Resources, Jul 2025]	4	101574393	101676375	Mouse	1346	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]
1316199	Leprotl1	leptin receptor overlapping transcript-like 1	Predicted to enable identical protein binding activity. Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway and negative regulation of growth hormone receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in endosome ... (more) . Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and respiratory system. Orthologous to human LEPROTL1 (leptin receptor overlapping transcript like 1). [provided by Alliance of Genome Resources, Jul 2025]	8	34602726	34613893	Mouse	87	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]