| 1556865 | Il22 | interleukin 22 | Enables cytokine activity. Involved in negative regulation of inflammatory response. Acts upstream of or within reactive oxygen species metabolic process and regulation of macromolecule metabolic process. Is active in extracellular space. Is expressed in ileum; retina; and skin. Used to study liposa rcoma. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL22 (interleukin 22). [provided by Alliance of Genome Resources, Apr 2025] | 10 | 118040456 | 118045952 | Mouse | 86 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1614980 | Il22b | interleukin 22B | Predicted to enable cytokine activity. Predicted to be involved in negative regulation of inflammatory response. Predicted to be active in extracellular space. Is expressed in retina. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL22 (interleukin 22). [provided by Alliance of Genome Resources, Apr 2025] | 10 | 118125534 | 118130943 | Mouse | 113 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1557122 | Il22ra1 | interleukin 22 receptor, alpha 1 | Enables interleukin-20 binding activity and interleukin-22 receptor activity. Involved in negative regulation of inflammatory response. Acts upstream of or within defense response to Gram-negative bacterium and negative regulation of cytokine production involved in inflammatory response. Predicted t o be active in plasma membrane. Is expressed in ileum. Orthologous to human IL22RA1 (interleukin 22 receptor subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 135455470 | 135482694 | Mouse | 100 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1322029 | Il22ra2 | interleukin 22 receptor, alpha 2 | Predicted to enable interleukin-22 binding activity and interleukin-22 receptor activity. Acts upstream of or within negative regulation of inflammatory response and regulation of tyrosine phosphorylation of STAT protein. Located in cytosol. Orthologous to human IL22 span>RA2 (interleukin 22 receptor subunit alpha 2). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 19497776 | 19510429 | Mouse | 66 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |