Il10 Gene Search Result

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3 records found for search term Il10

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
10785	Il10	interleukin 10	This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress a ... (more) utoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, Sep 2015]	1	130947459	130952707	Mouse	2122	array_id_rg_u34b_affymetrix , symbol , array_id_affy_mg_u74c_ensembl , PhenoGen , array_id_affy_mu11ksuba_ensembl , array_id_affy_mg_u74b_ensembl , array_id_affy_mg_u74av2_ensembl , array_id_rg_u34c_affymetrix , array_id_affy_mg_u74a_ensembl , array_id_rg_u34a_affymetrix , array_id_affy_mg_u74cv2_en ... (more) sembl , array_id_rn_u34_affymetrix , array_id_affy_mu11ksubb_ensembl , array_id_rt_u34_affymetrix , array_id_affy_mg_u74bv2_ensembl	gene, protein-coding, REVIEWED [RefSeq]
731001	Il10ra	interleukin 10 receptor, alpha	Predicted to enable interleukin-10 binding activity and interleukin-10 receptor activity. Predicted to be involved in several processes, including interleukin-10-mediated signaling pathway; intestinal epithelial structure maintenance; and ubiquitin-dependent endocytosis. Predicted to be located in c ... (more) ytosol. Predicted to be active in apical plasma membrane. Human ortholog(s) of this gene implicated in inflammatory bowel disease 28. Orthologous to human IL10RA (interleukin 10 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2025]	9	45165135	45180447	Mouse	198	symbol , PhenoGen , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1556884	Il10rb	interleukin 10 receptor, beta	Enables interleukin-10 receptor activity. Predicted to be involved in interleukin-10-mediated signaling pathway; positive regulation of cellular respiration; and positive regulation of receptor signaling pathway via JAK-STAT. Predicted to be located in membrane. Predicted to be active in plasma memb ... (more) rane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in graft-versus-host disease; hepatitis B; and inflammatory bowel disease 25. Orthologous to human IL10RB (interleukin 10 receptor subunit beta). [provided by Alliance of Genome Resources, Apr 2025]	16	91203166	91222718	Mouse	153	symbol , PhenoGen , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]