Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; HMG box domain binding activity; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation o
f angiogenesis; negative regulation of transcription by RNA polymerase II; and regulation of signal transduction. Acts upstream of or within several processes, including forebrain development; hepaticobiliary system development; and tube morphogenesis. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; gut; liver and biliary system; and metanephros. Orthologous to human HHEX (hematopoietically expressed homeobox). [provided by Alliance of Genome Resources, Jul 2025]
19
37423289
37429179
Mouse
334
symbol , old_gene_name , PhenoGen , description , old_gene_symbol