Enables PDZ domain binding activity. Involved in cellular response to reactive oxygen species; dendrite development; and positive regulation of MAPK cascade. Acts upstream of or within dopamine biosynthetic process; locomotion involved in locomotory behavior; and positive regulation of dopamine meta
bolic process. Is active in cell surface and synapse. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Orthologous to human GPR37 (G protein-coupled receptor 37). [provided by Alliance of Genome Resources, Jul 2025]
Predicted to enable G protein-coupled peptide receptor activity; peptide binding activity; and prosaposin receptor activity. Involved in cellular response to reactive oxygen species; negative regulation of systemic arterial blood pressure; and positive regulation of MAPK cascade. Acts upstream of or
within negative regulation of cell differentiation; negative regulation of smoothened signaling pathway; and positive regulation of cerebellar granule cell precursor proliferation. Located in plasma membrane. Is expressed in brain; dentate gyrus subgranular zone; spinal cord; spinal cord gray matter; and spinal cord white matter. Orthologous to human GPR37L1 (G protein-coupled receptor 37 like 1). [provided by Alliance of Genome Resources, Jul 2025]