| 10619 | Gapdh | glyceraldehyde-3-phosphate dehydrogenase | This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein was originally identified as a key glycolytic enzyme th at converts D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Subsequent studies have assigned a variety of additional functions to the protein including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Alternative splicing results in multiple transcript variants. Many pseudogenes similar to this locus are found throughout the mouse genome. [provided by RefSeq, Jan 2014] | 6 | 125138812 | 125143450 | Mouse | 610 | symbol , array_id_affy_mg_u74c_ensembl , PhenoGen , array_id_affy_mu11ksuba_ensembl , array_id_affy_mouse430a_2_ensembl , array_id_affy_moe430a_ensembl , array_id_affy_mg_u74b_ensembl , array_id_affy_mg_u74av2_ensembl , old_gene_name , array_id_affy_mouse430_2_ensembl , array_id_affy_mg_u74a_ensembl , array_id_affy_mg_u74cv2_ensembl , array_id_affy_moe430b_ensembl , array_id_affy_mu11ksubb_ensembl , array_id_affy_mg_u74bv2_ensembl | gene, protein-coding, VALIDATED [RefSeq] | | 15038031 | Gapdh-ps1 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 1 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 15037658 | Gapdh-ps2 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 2 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 15038103 | Gapdh-ps3 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 3 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 15037130 | Gapdh-ps4 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 4 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 15038314 | Gapdh-ps5 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 5 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 15037736 | Gapdh-ps6 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 6 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 15037483 | Gapdh-ps7 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 7 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 15038875 | Gapdh-ps8 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 8 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 15038394 | Gapdh-ps9 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 9 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 15037149 | Gapdh-ps10 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 10 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 15037847 | Gapdh-ps11 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 11 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 15037105 | Gapdh-ps12 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 12 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 15037930 | Gapdh-ps13 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 13 | | | | | Mouse | | symbol , PhenoGen | gene, pseudo | | 2301300 | Gapdh-ps14 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 14 | | 8 | 42061507 | 42062724 | Mouse | | symbol , PhenoGen | gene, pseudo, INFERRED [RefSeq] | | 7180613 | Gapdh-ps15 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 15 | Predicted to enable aspartic-type endopeptidase inhibitor activity; disordered domain specific binding activity; and identical protein binding activity. Predicted to be involved in several processes, including defense response to other organism; negative regulation of protein metabolic process; and positive regulation of canonical NF-kappaB signal transduction. Predicted to be located in several cellular components, including cytosol; lipid droplet; and nuclear membrane. Predicted to be part of GAIT complex and ribonucleoprotein complex. [provided by Alliance of Genome Resources, Apr 2025] | Y | 38575074 | 38576317 | Mouse | | symbol , array_id_affy_mg_u74c_ensembl , PhenoGen , array_id_affy_mu11ksuba_ensembl , array_id_affy_mouse430a_2_ensembl , array_id_affy_moe430a_ensembl , array_id_affy_mg_u74b_ensembl , array_id_affy_mg_u74av2_ensembl , array_id_affy_mouse430_2_ensembl , array_id_affy_mg_u74a_ensembl , array_id_affy _mg_u74cv2_ensembl , array_id_affy_moe430b_ensembl , array_id_affy_mu11ksubb_ensembl , array_id_affy_mg_u74bv2_ensembl | gene, pseudo, INFERRED [RefSeq] | | 2306332 | Gapdh-ps16 | glyceraldehyde-3-phosphate dehydrogenase, pseudogene 16 | | 8 | 93442374 | 93443574 | Mouse | | symbol , PhenoGen | gene, pseudo, INFERRED [RefSeq] | | 1550865 | Gapdhs | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic | Enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Involved in flagellated sperm motility. Acts upstream of or within glycolytic process. Located in sperm fibrous sheath and sperm principal piece. Is expressed in cerebral cortex; heart; and liver. Human ortholog(s) o f this gene implicated in Alzheimer's disease. Orthologous to human GAPDHS (glyceraldehyde-3-phosphate dehydrogenase, spermatogenic). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 30429204 | 30443106 | Mouse | 85 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] | | 2301292 | Gapdhrt | glyceraldehyde-3-phosphate dehydrogenase, retrotransposed | Predicted to enable several functions, including aspartic-type endopeptidase inhibitor activity; disordered domain specific binding activity; and glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in several processes, including defense response to o ther organism; intracellular signaling cassette; and negative regulation of protein metabolic process. Predicted to be located in several cellular components, including lipid droplet; microtubule cytoskeleton; and nuclear membrane. Predicted to be part of GAIT complex and ribonucleoprotein complex. Predicted to be active in cytosol; glutamatergic synapse; and postsynaptic density, intracellular component. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDH (glyceraldehyde-3-phosphate dehydrogenase). [provided by Alliance of Genome Resources, Apr 2025] | 14 | 11187822 | 11189022 | Mouse | 59 | symbol , PhenoGen , description | gene, pseudo, INFERRED [RefSeq] | | 2301302 | Gapdhrt2 | glyceraldehyde-3-phosphate dehydrogenase, retrotransposed 2 | Predicted to enable several functions, including aspartic-type endopeptidase inhibitor activity; disordered domain specific binding activity; and glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in several processes, including defense response to o ther organism; intracellular signaling cassette; and negative regulation of protein metabolic process. Predicted to be located in several cellular components, including lipid droplet; microtubule cytoskeleton; and nuclear membrane. Predicted to be part of GAIT complex and ribonucleoprotein complex. Predicted to be active in cytosol; glutamatergic synapse; and postsynaptic density, intracellular component. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDH (glyceraldehyde-3-phosphate dehydrogenase). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 76131965 | 76133165 | Mouse | 59 | symbol , PhenoGen , description | gene, pseudo, INFERRED [RefSeq] | | 1317928 | Iffo1 | intermediate filament family orphan 1 | Predicted to be involved in DNA double-strand break attachment to nuclear envelope; double-strand break repair via nonhomologous end joining; and protein localization to site of double-strand break. Predicted to be located in nuclear matrix; nucleoplasm; and site of double-strand break. Is expressed in diaphragm; embryo mesenchyme; and musculature. Orthologous to human IFFO1 (intermediate filament family orphan 1). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 125122167 | 125138746 | Mouse | 74 | array_id_affy_mg_u74av2_ensembl , array_id_affy_mg_u74c_ensembl , array_id_affy_mu11ksuba_ensembl , array_id_affy_mg_u74a_ensembl , array_id_affy_mg_u74cv2_ensembl , array_id_affy_mu11ksubb_ensembl , array_id_affy_mg_u74bv2_ensembl , array_id_affy_mg_u74b_ensembl | gene, protein-coding, VALIDATED [RefSeq] | |
