Fancb Gene Search Result

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

Advanced Search (OLGA)

Genes search result for Mus musculus
(View Results for all Objects and Ontologies)

2 records found for search term Fancb

Refine Term:

Assembly:

Chr

Sort By:

Export

RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1618957	Fancb	Fanconi anemia, complementation group B	Acts upstream of or within several processes, including bone marrow development; cellular response to camptothecin; and regulation of double-strand break repair via homologous recombination. Predicted to be located in chromatin. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed i ... (more) n cerebral cortex ventricular layer and cortical plate. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group B and head and neck squamous cell carcinoma. Orthologous to human FANCB (FA complementation group B). [provided by Alliance of Genome Resources, Jul 2025]	X	163763678	163780266	Mouse	126	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1614308	Fance	Fanconi anemia, complementation group E	This gene encodes the complementation group E subunit of the multimeric Fanconi anemia (FA) nuclear complex composed of proteins encoded by over ten Fanconi anemia complementation (FANC) group genes: FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE ... (more) , FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The FA complex is necessary for protection against DNA damage. This gene product is required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2. Defects in the related human gene are a cause of Fanconi anemia, a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. Translation of this protein is initiated at a non-AUG (CUG) start codon, which is inferred from the related human gene and the notion that this protein is functionally indispensable. Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2009]	17	28532504	28545548	Mouse	93	description	gene, protein-coding, REVIEWED [RefSeq]