Predicted to enable several functions, including dUTP diphosphatase activity; magnesium ion binding activity; and peroxisome proliferator activated receptor binding activity. Predicted to be involved in pyrimidine deoxyribonucleotide metabolic process and regulation of protein-containing complex ass
embly. Located in mitochondrion. Is expressed in central nervous system and retina. Orthologous to human DUT (deoxyuridine triphosphatase). [provided by Alliance of Genome Resources, Jul 2025]
2
125089168
125100969
Mouse
229
symbol , old_gene_name , PhenoGen , description , old_gene_symbol
Predicted to enable LRR domain binding activity; axon guidance receptor activity; and identical protein binding activity. Involved in several processes, including circulatory system development; neuron development; and regulation of gene expression. Acts upstream of or within several processes, incl
uding axon guidance; heart development; and mammary duct terminal end bud growth. Located in axolemma. Is expressed in several structures, including autopod; central nervous system; genitourinary system; jaw; and sensory organ. Used to study cystic kidney disease and lung cancer. Human ortholog(s) of this gene implicated in autosomal recessive congenital nystagmus; combined or isolated pituitary hormone deficiency 8; congenital nystagmus; multiple myeloma; and plasmacytoma. Orthologous to human ROBO1 (roundabout guidance receptor 1). [provided by Alliance of Genome Resources, Jul 2025]