| 1318830 | Creb3 | cAMP responsive element binding protein 3 | Enables sequence-specific DNA binding activity. Predicted to be involved in several processes, including positive regulation of chemotaxis; positive regulation of deacetylase activity; and positive regulation of defense response to virus by host. Predicted to be located in several cellular component s, including Golgi membrane; neuronal cell body; and nuclear body. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; genitourinary system; and skeleton. Orthologous to human CREB3 (cAMP responsive element binding protein 3). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 43562658 | 43567061 | Mouse | 198 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1550621 | Creb3l4 | cAMP responsive element binding protein 3-like 4 | This gene encodes a CREB (cyclic AMP-responsive element-binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein may play a role in adiposity and male germ cell development. Homozygous knockout mice for this gene show increased adipogenesis, elevated te sticular germ cell apoptosis and defects in spermatogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] | 3 | 90144805 | 90161387 | Mouse | 117 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1331877 | Crebrf | CREB3 regulatory factor | Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within maternal behavior; negative regulation of nuclear receptor-mediated glucocorticoid sig naling pathway; and positive regulation of prolactin signaling pathway. Located in nuclear body. Is expressed in blastocyst; early embryo; polar body; and uterus. Orthologous to human CREBRF (CREB3 regulatory factor). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 26918716 | 26995611 | Mouse | 183 | name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1552347 | Creb3l1 | cAMP responsive element binding protein 3-like 1 | Enables DNA-binding transcription activator activity, RNA polymerase II-specific; cAMP response element binding activity; and chromatin binding activity. Involved in several processes, including extracellular matrix constituent secretion; intracellular signal transduction; and negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Acts upstream of or within regulation of ossification. Located in endoplasmic reticulum. Is active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; lung; and skeleton. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 16. Orthologous to human CREB3L1 (cAMP responsive element binding protein 3 like 1). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 91812673 | 91854515 | Mouse | 176 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1550380 | Creb3l2 | cAMP responsive element binding protein 3-like 2 | Enables DNA-binding transcription activator activity, RNA polymerase II-specific and cAMP response element binding activity. Involved in chondrocyte differentiation; endoplasmic reticulum to Golgi vesicle-mediated transport; and positive regulation of transcription by RNA polymerase II. Predicted to be located in chromatin; nucleoplasm; and perinuclear endoplasmic reticulum. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; and genitourinary system. Orthologous to human CREB3L2 (cAMP responsive element binding protein 3 like 2). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 37307956 | 37419083 | Mouse | 185 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1317761 | Creb3l3 | cAMP responsive element binding protein 3-like 3 | Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Involved in positive regulation of transcription by RNA polymerase II and response to endop lasmic reticulum stress. Located in membrane and nucleus. Is expressed in several structures, including extraembryonic visceral endoderm; genitourinary system; gut; liver; and septum transversum. Orthologous to human CREB3L3 (cAMP responsive element binding protein 3 like 3). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 80920163 | 80934706 | Mouse | 180 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
