Predicted to enable ceramide binding activity. Acts upstream of or within several processes, including adult walking behavior; glutamate reuptake; and neurofilament cytoskeleton organization. Located in endoplasmic reticulum. Is expressed in several structures, including adrenal gland; gonad; hemoly
mphoid system gland; nervous system; and retina. Used to study neuronal ceroid lipofuscinosis 8. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 8 and neuronal ceroid lipofuscinosis 8 northern epilepsy variant. Orthologous to human CLN8 (CLN8 transmembrane ER and ERGIC protein). [provided by Alliance of Genome Resources, Jul 2025]
Enables disulfide oxidoreductase activity. Predicted to be involved in spliceosomal snRNP assembly. Located in Cajal body and female germ cell nucleus. Is expressed in brain; dorsal grey horn; and early conceptus. Orthologous to human COIL (coilin). [provided by Alliance of Genome Resources, Jul 202