Acts upstream of or within several processes, including camera-type eye development; positive regulation of cell differentiation; and positive regulation of intracellular signal transduction. Predicted to be located in cell surface and plasma membrane. Is expressed in several structures, including a
limentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study holoprosencephaly 11. Human ortholog(s) of this gene implicated in holoprosencephaly 11. Orthologous to human CDON (cell adhesion associated, oncogene regulated). [provided by Alliance of Genome Resources, Apr 2025]
Involved in positive regulation of myoblast differentiation. Acts upstream of or within axon guidance and smoothened signaling pathway. Located in growth cone and neuronal cell body. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and