Bcl2l1 Gene Search Result

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8 records found for search term Bcl2l1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1552009	Bcl2l1	BCL2-like 1	This gene encodes a member of the Bcl-2 family of apoptosis regulators. The encoded protein is localized to the inner and outer mitochondrial membranes and regulates the programmed cell death pathway during development and tissue homeostasis. This protein binds to voltage-dependent anion channels in ... (more) the outer mitochondrial membrane to facilitate the uptake of calcium ions. Mice embryos lacking this gene survived for two weeks and exhibited cell death of immature hematopoietic cells and neurons. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jan 2014]	2	152600652	152673632	Mouse	1498	symbol , PhenoGen	gene, protein-coding, REVIEWED [RefSeq]
731990	Bcl2l10	Bcl2-like 10	Enables identical protein binding activity. Involved in microtubule organizing center organization. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of intrinsic apoptotic signaling pathway; and positive regulation of a ... (more) poptotic process. Located in membrane and spindle. Is expressed in several structures, including early conceptus; genitourinary system; hemolymphoid system; liver; and meninges. Human ortholog(s) of this gene implicated in multiple myeloma; myelodysplastic syndrome; and stomach carcinoma. Orthologous to human BCL2L10 (BCL2 like 10). [provided by Alliance of Genome Resources, Jul 2025]	9	75255040	75258922	Mouse	117	symbol , PhenoGen , description	gene, protein-coding, PROVISIONAL [RefSeq]
734300	Bcl2l11	BCL2 like 11	Enables microtubule binding activity and protein kinase binding activity. Involved in response to endoplasmic reticulum stress. Acts upstream of or within several processes, including apoptotic signaling pathway; hematopoietic or lymphoid organ development; and lymphocyte homeostasis. Located in mem ... (more) brane and mitochondrion. Part of Bcl-2 family protein complex. Is expressed in several structures, including hair outer root sheath; hemolymphoid system gland; metanephros; neural tube; and trunk mesenchyme. Orthologous to human BCL2L11 (BCL2 like 11). [provided by Alliance of Genome Resources, Jul 2025]	2	127967958	128004467	Mouse	725	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1316515	Bcl2l12	BCL2 like 12	Enables p53 binding activity. Acts upstream of or within negative regulation of cellular senescence and negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Predicted to be located in nucleus. Is expressed in several structures, including adre ... (more) nal gland; genitourinary system; gut; quadriceps femoris muscle; and respiratory system. Orthologous to human BCL2L12 (BCL2 like 12). [provided by Alliance of Genome Resources, Jul 2025]	7	44640646	44647011	Mouse	88	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1315912	Bcl2l13	BCL2 like 13	Acts upstream of or within several processes, including canonical glycolysis; fat cell differentiation; and mitophagy. Is active in mitochondrion. Orthologous to human BCL2L13 (BCL2 like 13). [provided by Alliance of Genome Resources, Apr 2025]	6	120813167	120869803	Mouse	127	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1557691	Bcl2l14	BCL2 like 14	Predicted to enable protein kinase binding activity. Predicted to be involved in apoptotic process and positive regulation of extrinsic apoptotic signaling pathway. Predicted to act upstream of or within regulation of apoptotic process. Predicted to be located in cytosol. Is expressed in early embry ... (more) o; genitourinary system; gut; and submandibular gland primordium. Orthologous to human BCL2L14 (BCL2 like 14). [provided by Alliance of Genome Resources, Apr 2025]	6	134373292	134415687	Mouse	110	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
2302590	Bcl2l15	BCLl2-like 15	Predicted to be involved in regulation of apoptotic process. Located in cytosol and nucleus. Orthologous to human BCL2L15 (BCL2 like 15). [provided by Alliance of Genome Resources, Jul 2025]	3	103738331	103761934	Mouse	70	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1624440	Morrbid	myeloid RNA regulator of BCL2L11 induced cell death	Orthologous to human MIR4435-2HG (MIR4435-2 host gene). [provided by Alliance of Genome Resources, Jul 2025]	2	128140583	128271271	Mouse	43	name	gene, ncrna, VALIDATED [RefSeq]