Atg12 Gene Search Result

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6 records found for search term Atg12

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1558563	Atg12	autophagy related 12	Predicted to enable protein tag activity. Predicted to contribute to Atg8-family ligase activity. Involved in autophagosome assembly; negative regulation of defense response; and negative regulation of type I interferon production. Located in phagophore assembly site membrane. Part of Atg12 ... (more) ont-weight:700;'>Atg12-Atg5-Atg16 complex. Is expressed in central nervous system; dorsal root ganglion; heart; lower jaw molar; and retina. Orthologous to human ATG12 (autophagy related 12). [provided by Alliance of Genome Resources, Jul 2025]	18	46865484	46874683	Mouse	238	symbol , old_gene_name , PhenoGen , description , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1558502	Atg7	autophagy related 7	This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon mem ... (more) brane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]	6	114620075	114837565	Mouse	623	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]
1557023	Atg10	autophagy related 10	Enables Atg12 conjugating enzyme activity. Acts upstream of or within positive regulation of protein modification process and protein lipidation. Predicted to be located in cytosol. Orthologous to human ATG10 (autophagy related 10). [provided by Alliance of Geno ... (more) me Resources, Jul 2025]	13	91083467	91372189	Mouse	134	description	gene, protein-coding, VALIDATED [RefSeq]
1553543	Atg16l1	autophagy related 16 like 1	Enables identical protein binding activity. Involved in several processes, including autophagosome assembly; axonal transport; and defense response to virus. Acts upstream of or within macroautophagy; negative stranded viral RNA replication; and telencephalon development. Located in several cellular ... (more) components, including autophagosome membrane; phagophore assembly site membrane; and sperm midpiece. Part of Atg12-Atg5-Atg16 complex. Is active in glutamatergic synapse. Is expressed in central nervous system and retina. Used to study inflammatory bowel disease 10. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Orthologous to human ATG16L1 (autophagy related 16 like 1). [provided by Alliance of Genome Resources, Jul 2025]	1	87683730	87720150	Mouse	264	description	gene, protein-coding, VALIDATED [RefSeq]
1617481	Atg16l2	autophagy related 16 like 2	Involved in autophagosome assembly. Acts upstream of or within negative stranded viral RNA replication. Located in cytosol and phagophore assembly site membrane. Part of Atg12-Atg5-Atg16 complex. Is expressed in embryo. Orthologous to human ATG16L2 (autophagy re ... (more) lated 16 like 2). [provided by Alliance of Genome Resources, Jul 2025]	7	100935521	100951474	Mouse	100	description	gene, protein-coding, VALIDATED [RefSeq]
1557224	Atg3	autophagy related 3	Enables Atg12 transferase activity and Atg8-family ligase activity. Involved in autophagosome assembly; mitochondrial fragmentation involved in apoptotic process; and regulation of cilium assembly. Acts upstream of or within macroautophagy and negative regulatio ... (more) n of phagocytosis. Predicted to be part of Atg12-Atg5-Atg16 complex and cytoplasmic ubiquitin ligase complex. Predicted to be active in cytosol and phagophore assembly site. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human ATG3 (autophagy related 3). [provided by Alliance of Genome Resources, Jul 2025]	16	44979192	45008901	Mouse	192	description	gene, protein-coding, VALIDATED [RefSeq]