Predicted to enable several functions, including alkaline phosphatase activity; metal ion binding activity; and protein homodimerization activity. Acts upstream of or within cellular response to BMP stimulus. Predicted to be located in external side of plasma membrane. Predicted to be active in extr
acellular space and plasma membrane. Is expressed in intestine; palatal shelf mesenchyme; and testis. Human ortholog(s) of this gene implicated in inflammatory bowel disease. Orthologous to several human genes including ALPG (alkaline phosphatase, germ cell) and ALPI (alkaline phosphatase, intestinal). [provided by Alliance of Genome Resources, Jul 2025]
alkaline phosphatase 3, intestine, not Mn requiring
Predicted to enable alkaline phosphatase activity; metal ion binding activity; and protease binding activity. Acts upstream of or within neural tube development; neurogenesis; and post-anal tail morphogenesis. Located in brush border. Is expressed in duodenum; intestine; and jejunum. Human ortholog(
s) of this gene implicated in inflammatory bowel disease. Orthologous to several human genes including ALPG (alkaline phosphatase, germ cell) and ALPI (alkaline phosphatase, intestinal). [provided by Alliance of Genome Resources, Jul 2025]
Enables alkaline phosphatase activity. Located in myofibril. Is expressed in early conceptus; intestine; and testis. Human ortholog(s) of this gene implicated in inflammatory bowel disease. Orthologous to human ALPG (alkaline phosphatase, germ cell); ALPI (alkal