Tbk1 Gene Search Result

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6 records found for search term Tbk1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1313752	TBK1	TANK binding kinase 1	The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and ... (more) nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein is also an important kinase for antiviral innate immunity response. [provided by RefSeq, Sep 2021]	12	64452120	64502114	Human	521	symbol , old_gene_name , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
731934	TBKBP1	TBK1 binding protein 1	TBKBP1 is an adaptor protein that binds to TBK1 (MIM 604834) and is part of the interaction network in the TNF (MIM 191160)/NFKB (see MIM 164011) pathway (Bouwmeester et al., 2004 [PubMed 14743216]).[supplied by OMIM, Mar 2008]	17	47694063	47712063	Human	74	old_gene_name , name , description	gene, protein-coding, VALIDATED [RefSeq]
16568374	AC135279.3	novel transcript, antisense to TBK1					Human		name	gene, lncrna
1606546	CC2D1A	coiled-coil and C2 domain containing 1A	This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A m ... (more) utation in this gene results in a nonsyndromic form of cognitive disability (MRT3). [provided by RefSeq, Jul 2017]	19	13906201	13930879	Human	147	old_gene_name	gene, protein-coding, REVIEWED [RefSeq]
1605352	AZI2	5-azacytidine induced 2	AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008]	3	28321047	28348824	Human	82	description	gene, protein-coding, VALIDATED [RefSeq]
1602207	SIKE1	suppressor of IKBKE 1	SIKE interacts with IKK-epsilon (IKBKE; MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008]	1	114769479	114780685	Human	54	description	gene, protein-coding, VALIDATED [RefSeq]