| 68962 | SNX1 | sorting nexin 1 | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] | 15 | 64095982 | 64144231 | Human | 161 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1314019 | SNX10 | sorting nexin 10 | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene may play a rol e in regulating endosome homeostasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010] | 7 | 26291862 | 26374383 | Human | 289 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1316444 | SNX11 | sorting nexin 11 | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene encodes a prot ein of unknown function. This gene results in two transcript variants differing in the 5' UTR, but encoding the same protein. [provided by RefSeq, Jul 2008] | 17 | 48107574 | 48123601 | Human | 65 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1350610 | SNX12 | sorting nexin 12 | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. A similar protein in mou se may be involved in regulating the neurite outgrowth. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] | X | 71059247 | 71073426 | Human | 82 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320299 | SNX13 | sorting nexin 13 | This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008] | 7 | 17790761 | 17940494 | Human | 72 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1322101 | SNX14 | sorting nexin 14 | This gene encodes a member of the sorting nexin family. Members of this family have a phox (PX) phosphoinositide binding domain and are involved in intracellular trafficking. The encoded protein also contains a regulator of G protein signaling (RGS) domain. Regulator of G protein signaling family me mbers are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. Alternate splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014] | 6 | 85505496 | 85593858 | Human | 177 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1314058 | SNX15 | sorting nexin 15 | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth f actor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene. [provided by RefSeq, Dec 2010] | 11 | 65027439 | 65040572 | Human | 72 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 733907 | SNX16 | sorting nexin 16 | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The protein encoded by this gene associates with late endosome membranes as is involved in tubule form ation, cholesterol transport, and transport of tetraspanin CD81. The encoded protein also inhibits cell migration and tumorigenesis. [provided by RefSeq, Jan 2017] | 8 | 81799583 | 81842185 | Human | 103 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1315030 | SNX17 | sorting nexin 17 | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domai n. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012] | 2 | 27370616 | 27377535 | Human | 103 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1321231 | SNX18 | sorting nexin 18 | This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domai n. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 5 | 54517759 | 54648005 | Human | 122 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1604682 | SNX19 | sorting nexin 19 | Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabiliz ing the number of dense-core secretory vesicles. [provided by RefSeq, Dec 2016] | 11 | 130866250 | 130916479 | Human | 68 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 5129009 | SNX18P2 | sorting nexin 18 pseudogene 2 | INTERACTS WITH cadmium dichloride | 9 | 92893668 | 92894505 | Human | 1 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128991 | SNX18P3 | sorting nexin 18 pseudogene 3 | INTERACTS WITH ethylparaben; lipopolysaccharide; S-(1,2-dichlorovinyl)-L-cysteine | 9 | 38567401 | 38569182 | Human | 4 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128989 | SNX18P4 | sorting nexin 18 pseudogene 4 | | 9 | 66082385 | 66083772 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128988 | SNX18P5 | sorting nexin 18 pseudogene 5 | | 9 | 42922701 | 42924096 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 5128983 | SNX18P7 | sorting nexin 18 pseudogene 7 | INTERACTS WITH benzo[a]pyrene; cadmium dichloride | 9 | 33575502 | 33577014 | Human | 2 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128986 | SNX18P8 | sorting nexin 18 pseudogene 8 | INTERACTS WITH cadmium dichloride | 9 | 40292534 | 40293921 | Human | 1 | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5129007 | SNX18P9 | sorting nexin 18 pseudogene 9 | | 9 | 64439032 | 64440151 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1352467 | SNX19P1 | sorting nexin 19 pseudogene 1 | | 21 | 13525103 | 13530011 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 3362733 | SNX19P2 | sorting nexin 19 pseudogene 2 | | 13 | 18890800 | 18895740 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 3029010 | SNX19P3 | sorting nexin 19 pseudogene 3 | | 18 | 14628383 | 14633302 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5131797 | SNX19P4 | sorting nexin 19 pseudogene 4 | | 10 | 72483227 | 72483855 | Human | | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128980 | SNX18P10 | sorting nexin 18 pseudogene 10 | | 21 | 8801140 | 8801893 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128969 | SNX18P11 | sorting nexin 18 pseudogene 11 | | 21 | 9092853 | 9093808 | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128971 | SNX18P12 | sorting nexin 18 pseudogene 12 | | 21 | 9364259 | 9364828 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 329955661 | SNX18P12 | sorting nexin 18 pseudogene 12 | | | | | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128970 | SNX18P13 | sorting nexin 18 pseudogene 13 | INTERACTS WITH aristolochic acid A | 21 | 13905738 | 13907320 | Human | 1 | symbol , COSMIC , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 5128990 | SNX18P14 | sorting nexin 18 pseudogene 14 | | 2 | 94786472 | 94787944 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128978 | SNX18P15 | sorting nexin 18 pseudogene 15 | | | | | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128981 | SNX18P16 | sorting nexin 18 pseudogene 16 | | | | | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128975 | SNX18P17 | sorting nexin 18 pseudogene 17 | | | | | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128979 | SNX18P18 | sorting nexin 18 pseudogene 18 | | | | | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128977 | SNX18P19 | sorting nexin 18 pseudogene 19 | INTERACTS WITH mercury dibromide; phenylmercury acetate | | | | Human | 2 | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 5128987 | SNX18P1Y | sorting nexin 18 pseudogene 1, Y-linked | | Y | 11178593 | 11179239 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128974 | SNX18P20 | sorting nexin 18 pseudogene 20 | | | | | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 5128976 | SNX18P21 | sorting nexin 18 pseudogene 21 | | | | | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128972 | SNX18P22 | sorting nexin 18 pseudogene 22 | | | | | Human | | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 6484032 | SNX18P23 | sorting nexin 18 pseudogene 23 | | 4 | 49232915 | 49233959 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128982 | SNX18P24 | sorting nexin 18 pseudogene 24 | | 4 | 49560650 | 49562149 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 5128984 | SNX18P25 | sorting nexin 18 pseudogene 25 | | 4 | 49588774 | 49589728 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 5128973 | SNX18P26 | sorting nexin 18 pseudogene 26 | | 13 | 18807276 | 18808855 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 6481549 | SNX18P27 | sorting nexin 18 pseudogene 27 | | 8 | 43513643 | 43514421 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 16553290 | SNX10-AS1 | SNX10 antisense RNA 1 | | 7 | 26372019 | 26399418 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 7370113 | ARL2-SNX15 | ARL2-SNX15 readthrough (NMD candidate) | This locus represents naturally occurring read-through transcription between the neighboring ADP-ribosylation factor-like 2 (ARL2) and sorting nexin 15 (SNX15) genes on chromosome 11. The read-through transcript is a candidate for nonsense-mediated mRNA decay (N MD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Dec 2010] | 11 | 65014160 | 65040572 | Human | 8 | symbol , COSMIC , name , description , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1317589 | DNAJC13 | DnaJ heat shock protein family (Hsp40) member C13 | This gene encodes a member of the Dnaj protein family whose members act as co-chaperones of a partner heat-shock protein by binding to the latter and stimulating ATP hydrolysis. The encoded protein associates with the heat-shock protein Hsc70 and plays a role in clathrin-mediated endocytosis. It may also be involved in post-endocytic transport mechanisms via its associations with other proteins, including the sorting nexin SNX1. Mutations in this gene are associated with Parkinson's disease. [provided by RefSeq, Jun 2016] | 3 | 132417502 | 132539032 | Human | 128 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 16565995 | AC011477.5 | sorting nexin 18 (SNX18) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16558634 | AC118282.3 | sorting nexin 18 (SNX18) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16559329 | AC119751.6 | sorting nexin 18 (SNX18) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16568099 | AL445670.1 | sorting nexin 18 (SNX18) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16567125 | AP005212.2 | sorting nexin 18 (SNX18) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16559698 | AC132219.1 | novel transcript, antisense to SNX16 | | | | | Human | | name | gene, lncrna |
| 1313857 | SYNCRIP | synaptotagmin binding cytoplasmic RNA interacting protein | This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded p rotein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20. [provided by RefSeq, Dec 2011] | 6 | 85607784 | 85643870 | Human | 221 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
