Smg5 Gene Search Result

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Genes search result for Homo sapiens
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3 records found for search term Smg5

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1603683	SMG5	SMG5 nonsense mediated mRNA decay factor	SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM, Mar 2008]	1	156249224	156291516	Human	77	symbol , old_gene_name , COSMIC , name , description , Human Proteome Map	gene, protein-coding, VALIDATED [RefSeq]
16560581	AC023245.2	Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) (SMG5) pseudogene		8	109777938	109782261	Human		old_gene_name , name	gene, pseudo, INFERRED [RefSeq]
1321852	SMG7	SMG7 nonsense mediated mRNA decay factor	This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 ... (more) 'font-weight:700;'>SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2011]	1	183472499	183554191	Human	79	description	gene, protein-coding, REVIEWED [RefSeq]