Slc8a1 Gene Search Result

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3 records found for search term Slc8a1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
731021	SLC8A1	solute carrier family 8 member A1	In cardiac myocytes, Ca(2+) concentrations alternate between high levels during contraction and low levels during relaxation. The increase in Ca(2+) concentration during contraction is primarily due to release of Ca(2+) from intracellular stores. However, some Ca(2+) also enters the cell through the ... (more) sarcolemma (plasma membrane). During relaxation, Ca(2+) is sequestered within the intracellular stores. To prevent overloading of intracellular stores, the Ca(2+) that entered across the sarcolemma must be extruded from the cell. The Na(+)-Ca(2+) exchanger is the primary mechanism by which the Ca(2+) is extruded from the cell during relaxation. In the heart, the exchanger may play a key role in digitalis action. The exchanger is the dominant mechanism in returning the cardiac myocyte to its resting state following excitation.[supplied by OMIM, Apr 2004]	2	40097270	40512435	Human	403	symbol , COSMIC , Human Proteome Map	gene, protein-coding, VALIDATED [RefSeq]
6767272	SLC8A1-AS1	SLC8A1 antisense RNA 1	INTERACTS WITH antirheumatic drug; diuron	2	39917634	40255209	Human	2	symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]
38670602	LOC101929667	uncharacterized LOC101929667		2	40511922	40558453	Human		old_gene_name	gene, ncrna, MODEL [RefSeq]