| 731475 | SLC6A1 | solute carrier family 6 member 1 | The protein encoded by this gene is a gamma-aminobutyric acid (GABA) transporter that localizes to the plasma membrane. The encoded protein removes GABA from the synaptic cleft, restoring it to presynaptic terminals. [provided by RefSeq, Jan 2017] | 3 | 10992748 | 11039247 | Human | 922 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 6481296 | SLC6A1-AS1 | SLC6A1 antisense RNA 1 | | 3 | 11006098 | 11019224 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 732372 | SLC6A11 | solute carrier family 6 member 11 | The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants e ncoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] | 3 | 10816228 | 10940714 | Human | 120 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 731509 | SLC6A12 | solute carrier family 6 member 12 | Enables gamma-aminobutyric acid:sodium:chloride symporter activity. Involved in gamma-aminobutyric acid transport and monocarboxylic acid transport. Predicted to be located in basolateral plasma membrane. Predicted to be active in cell projection and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 12 | 183848 | 214157 | Human | 163 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 733725 | SLC6A13 | solute carrier family 6 member 13 | Enables gamma-aminobutyric acid:sodium:chloride symporter activity. Involved in amino acid import across plasma membrane and monocarboxylic acid transport. Located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] | 12 | 220622 | 262836 | Human | 165 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1347984 | SLC6A14 | solute carrier family 6 member 14 | This gene encodes a member of the solute carrier family 6. Members of this family are sodium and chloride dependent neurotransmitter transporters. The encoded protein transports both neutral and cationic amino acids. This protein may also function as a beta-alanine carrier. Mutations in this gene ma y be associated with X-linked obesity. A pseudogene of this gene is found on chromosome X.[provided by RefSeq, May 2010] | X | 116436606 | 116461458 | Human | 163 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 735866 | SLC6A15 | solute carrier family 6 member 15 | This gene encodes a member of the solute carrier family 6 protein family which transports neutral amino acids. The encoded protein is thought to play a role in neuronal amino acid transport (PMID: 16185194) and may be associated with major depression (PMID: 21521612). Multiple transcript variants en coding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] | 12 | 84859491 | 84912799 | Human | 141 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1353315 | SLC6A16 | solute carrier family 6 member 16 | SLC6A16 shows structural characteristics of an Na(+)- and Cl(-)-dependent neurotransmitter transporter, including 12 transmembrane (TM) domains, intracellular N and C termini, and large extracellular loops containing multiple N-glycosylation sites.[supplied by O MIM, Mar 2008] | 19 | 49289638 | 49340330 | Human | 53 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1603474 | SLC6A17 | solute carrier family 6 member 17 | The protein encoded by this gene is a member of the SLC6 family of transporters, which are responsible for the presynaptic uptake of most neurotransmitters. The encoded vesicular transporter is selective for proline, glycine, leucine and alanine. In mouse, the strongest expression of this gene was i n cortical and hippocampal tissues where expression increased during embryonic brain development and peaked postnatally. Defects in this gene cause a form of autosomal recessive intellectual disability. [provided by RefSeq, Jul 2017] | 1 | 110150494 | 110202202 | Human | 124 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1346320 | SLC6A18 | solute carrier family 6 member 18 | The SLC6 family of proteins, which includes SLC6A18, act as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).[supplied by OMIM, Apr 2010] | 5 | 1225381 | 1246189 | Human | 82 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1604954 | SLC6A19 | solute carrier family 6 member 19 | This gene encodes a system B(0) transmembrane protein that actively transports most neutral amino acids across the apical membrane of epithelial cells. Mutations in this gene may result in Hartnup disorder, an inherited disease with symptoms such as pellagra, cerebellar ataxia, and psychosis. The ex pression and function of B0AT1 (SLC6A19) in intestinal cells depends on the presence of the accessory protein angiotensin-converting enzyme 2 (ACE2) which, among other functions, acts as a chaperone for membrane trafficking of B0AT1. The ACE2 is also the cellular receptor for severe acute respiratory syndrome-coronavirus (SARS-CoV) and for SARS-CoV-2 that is causing the coronavirus 2019 (COVID-19) pandemic [provided by RefSeq, Jul 2020] | 5 | 1201595 | 1225111 | Human | 226 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1343735 | SLC6A10P | solute carrier family 6 member 10, pseudogene | INTERACTS WITH 2-hydroxypropanoic acid; 2-methylcholine; acrylamide | 16 | 32877473 | 32885142 | Human | 16 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, VALIDATED [RefSeq] |
| 38673470 | SLC6A10PB | solute carrier family 6 member 8 pseudogene | INTERACTS WITH bisphenol A; trichostatin A; valproic acid | | | | Human | 3 | symbol , GTEx , COSMIC , Human Proteome Map | gene, pseudo, MODEL [RefSeq] |
| 14989406 | SLC6A14P1 | SLC6A14 pseudogene 1 | | X | 116669810 | 116678273 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 14993716 | SLC6A14P2 | SLC6A14 pseudogene 2 | | X | 116688830 | 116692685 | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 14987326 | SLC6A14P3 | SLC6A14 pseudogene 3 | | 2 | 126311408 | 126311953 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 25330325 | SLC6A12-AS1 | SLC6A12 antisense RNA 1 | | 12 | 203645 | 205093 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 25330224 | SLC6A17-AS1 | SLC6A17 antisense RNA 1 | | 1 | 110165948 | 110168851 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16572058 | AC027128.1 | novel transcript, antisense to SLC6A11 | | | | | Human | | name | gene, lncrna |
| 16556982 | BX119904.4 | pseudogene similar to part of solute carrier family 6 (neurotransmitter transporter), member 14 (SLC6A14) | | | | | Human | | name | gene, unprocessed_pseudogene |
