Sesn1 Gene Search Result

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2 records found for search term Sesn1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1316757	SESN1	sestrin 1	This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results ... (more) in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]	6	108984309	109094846	Human	214	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
16566096	AL390208.1	novel transcript, antisense to SESN1					Human		name	gene, lncrna