Robo1 Gene Search Result

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Genes search result for Homo sapiens
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3 records found for search term Robo1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
735617	ROBO1	roundabout guidance receptor 1	Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immu ... (more) noglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]	3	78597239	79767998	Human	379	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
16573171	AC117461.1	novel transcript, antisense to ROBO1					Human		name	gene, lncrna
1348930	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1	The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42. [provided by RefSeq, Sep 2016]	12	63844700	64162217	Human	128	description	gene, protein-coding, REVIEWED [RefSeq]