Psmc1 Gene Search Result

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14 records found for search term Psmc1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
734425	PSMC1	proteasome 26S subunit, ATPase 1	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. T ... (more) he 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit and a 20S core alpha subunit interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. This subunit also interacts with the adenovirus E1A protein and this interaction alters the activity of the proteasome. Finally, this subunit interacts with ataxin-7, suggesting a role for the proteasome in the development of spinocerebellar ataxia type 7, a progressive neurodegenerative disorder. [provided by RefSeq, Jul 2008]	14	90256553	90275429	Human	188	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1348724	PSMC1P1	proteasome 26S subunit, ATPase 1 pseudogene 1	INTERACTS WITH lead diacetate	3	68635707	68637247	Human	1	symbol , COSMIC , Human Proteome Map , old_gene_symbol	gene, pseudo, INFERRED [RefSeq]
5130613	PSMC1P2	proteasome 26S subunit, ATPase 1 pseudogene 2		7	27461711	27463189	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
5130615	PSMC1P3	proteasome 26S subunit, ATPase 1 pseudogene 3		7	136713873	136715412	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
5130618	PSMC1P4	proteasome 26S subunit, ATPase 1 pseudogene 4		5	56275075	56276626	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
10412462	PSMC1P5	proteasome 26S subunit, ATPase 1 pseudogene 5		5	107195156	107195332	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
5130602	PSMC1P6	proteasome 26S subunit, ATPase 1 pseudogene 6		3	87630078	87631623	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
5130600	PSMC1P7	proteasome 26S subunit, ATPase 1 pseudogene 7	INTERACTS WITH propanal	3	161328705	161330236	Human	1	symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
5130616	PSMC1P8	proteasome 26S subunit, ATPase 1 pseudogene 8		12	17383113	17384645	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
5130445	PSMC1P9	proteasome 26S subunit, ATPase 1 pseudogene 9	INTERACTS WITH tunicamycin	12	18692759	18694323	Human	1	symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
5130617	PSMC1P10	proteasome 26S subunit, ATPase 1 pseudogene 10		2	17385093	17386634	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
5130614	PSMC1P11	proteasome 26S subunit, ATPase 1 pseudogene 11		6	4702457	4704003	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
5130601	PSMC1P12	proteasome 26S subunit, ATPase 1 pseudogene 12		1	118614107	118615644	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
5130571	PSMC1P13	proteasome 26S subunit, ATPase 1 pseudogene 13		13	69893856	69895367	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]