Prkar2a Gene Search Result

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3 records found for search term Prkar2a

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
732434	PRKAR2A	protein kinase cAMP-dependent type II regulatory subunit alpha	cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulato ... (more) ry and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq, Jul 2008]	3	48744591	48847874	Human	219	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
5144653	PRKAR2A-AS1	PRKAR2A antisense RNA 1		3	48847937	48851982	Human		symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]
16560473	AP001636.2	cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A) pseudogene		11	58967596	58968291	Human		name	gene, pseudo, INFERRED [RefSeq]