Nr1h2 Gene Search Result

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3 records found for search term Nr1h2

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1352469	NR1H2	nuclear receptor subfamily 1 group H member 2	The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal ... (more) gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010]	19	50376457	50383388	Human	306	symbol , COSMIC , Human Proteome Map	gene, protein-coding, VALIDATED [RefSeq]
16565173	NR1H2-AS1	NR1H2 antisense RNA 1					Human		symbol , old_gene_name , COSMIC , name , Human Proteome Map	gene, lncrna
1347374	NAPSA	napsin A aspartic peptidase	This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These pep ... (more) tide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]	19	50358477	50369302	Human	109	old_gene_name , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]