Nfx1 Gene Search Result

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2 records found for search term Nfx1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1321083	NFX1	nuclear transcription factor, X-box binding 1	MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding ... (more) to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified. [provided by RefSeq, Jul 2008]	9	33290516	33371157	Human	117	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1603622	ZNFX1	zinc finger NFX1-type containing 1	Enables RNA binding activity. Involved in defense response to bacterium and defense response to virus. Is active in cytoplasmic stress granule. Implicated in immunodeficiency 91. [provided by Alliance of Genome Resources, Jul 2025]	20	49245900	49278057	Human	150	symbol , old_gene_name , COSMIC , name , Human Proteome Map	gene, protein-coding, VALIDATED [RefSeq]