Nfkb2 Gene Search Result

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4 records found for search term Nfkb2

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1316230	NFKB2	nuclear factor kappa B subunit 2	This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a tran ... (more) scriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]	10	102394110	102402529	Human	399	symbol , old_gene_name , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
16564600	AP001017.1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2) pseudogene					Human		name	gene, processed_pseudogene
16564665	AP002414.3	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) (NFKB2) pseudogene		18	12091518	12093086	Human		name	gene, pseudo, INFERRED [RefSeq]
1352761	RELA	RELA proto-oncogene, NF-kB subunit	NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed ... (more) of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]	11	65653601	65663857	Human	3120	description	gene, protein-coding, REVIEWED [RefSeq]