Nedd4l Gene Search Result

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5 records found for search term Nedd4l

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1344203	NEDD4L	NEDD4 like E3 ubiquitin protein ligase	This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitina ... (more) tion of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]	18	58044226	58401540	Human	406	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
625784267	NEDD4L-AS1	NEDD4L antisense RNA 1					Human		symbol , GTEx , COSMIC , name , Human Proteome Map	gene, ncrna
16564615	AC090236.1	novel transcript, antisense to NEDD4L					Human		name	gene, lncrna
16564677	AC090236.2	novel transcript, sense intronic to NEDD4L					Human		name	gene, lncrna
16564818	AC107896.1	uncharacterized LOC105372143		18	58189834	58195710	Human		old_gene_name	gene, ncrna, VALIDATED [RefSeq]