| 1344668 | NAT1 | N-acetyltransferase 1 | This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabo lize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] | 8 | 18170467 | 18223689 | Human | 209 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1313238 | EIF4G2 | eukaryotic translation initiation factor 4 gamma 2 | Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-termin al region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008] | 11 | 10797046 | 10808926 | Human | 154 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 730997 | SLC38A3 | solute carrier family 38 member 3 | Enables L-amino acid transmembrane transporter activity. Involved in carboxylic acid transport. Located in plasma membrane. Implicated in developmental and epileptic encephalopathy 102. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 50205271 | 50221486 | Human | 291 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 731947 | SLC6A2 | solute carrier family 6 member 2 | This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic in tolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010] | 16 | 55655988 | 55706192 | Human | 281 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1605376 | NAT10 | N-acetyltransferase 10 | The protein encoded by this gene is an RNA cytidine acetyltransferase involved in histone acetylation, tRNA acetylation, the biosynthesis of 18S rRNA, and the enhancement of nuclear architecture and chromatin organization. [provided by RefSeq, Oct 2016] | 11 | 34105629 | 34146908 | Human | 137 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1601749 | NAT14 | N-acetyltransferase 14 (putative) | Predicted to enable N-acetyltransferase activity. Predicted to be involved in DNA-templated transcription initiation and positive regulation of DNA-templated transcription. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 19 | 55485188 | 55487566 | Human | 49 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1601690 | NAT16 | N-acetyltransferase 16 (putative) | Predicted to enable acyltransferase activity, transferring groups other than amino-acyl groups. [provided by Alliance of Genome Resources, Jul 2025] | 7 | 101170496 | 101180293 | Human | 22 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1343133 | NAA15 | N-alpha-acetyltransferase 15, NatA auxiliary subunit | N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes the a uxillary subunit of the N-terminal acetyltransferase A (NatA) complex. [provided by RefSeq, Jan 2017] | 4 | 139301505 | 139391384 | Human | 210 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1346528 | NAA30 | N-alpha-acetyltransferase 30, NatC catalytic subunit | Enables protein-N-terminal amino-acid acetyltransferase activity. Involved in protein stabilization. Located in cytosol and nucleus. Part of NatC complex. [provided by Alliance of Genome Resources, Jul 2025] | 14 | 57390586 | 57415906 | Human | 74 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1602685 | NAA40 | N-alpha-acetyltransferase 40, NatD catalytic subunit | Enables histone H2A acetyltransferase activity; histone H4 acetyltransferase activity; and protein N-terminal-serine acetyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within lipid metabolic process. Located in centriolar satellite; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 11 | 63939002 | 63957319 | Human | 75 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1322131 | NAA50 | N-alpha-acetyltransferase 50, NatE catalytic subunit | Enables histone H4 acetyltransferase activity and protein-N-terminal amino-acid acetyltransferase activity. Involved in N-terminal protein amino acid acetylation; establishment of mitotic sister chromatid cohesion; and mitotic sister chromatid cohesion, centromeric. Located in cytosol and nucleolus. Part of NatA complex. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 113716458 | 113746249 | Human | 112 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1605347 | NAA60 | N-alpha-acetyltransferase 60, NatF catalytic subunit | This gene encodes an enzyme that localizes to the Golgi apparatus, where it transfers an acetyl group to the N-terminus of free proteins. This enzyme acts on histones, and its activity is important for chromatin assembly and chromosome integrity. Alternative splicing and the use of alternative promo ters results in multiple transcript variants. The upstream promoter is located in a differentially methylated region (DMR) and undergoes imprinting; transcript variants originating from this position are expressed from the maternal allele. [provided by RefSeq, Nov 2015] | 16 | 3443611 | 3486963 | Human | 162 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 732527 | NAT2 | N-acetyltransferase 2 | This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polym orphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second polymorphic arylamine N-acetyltransferase gene (NAT1), is located near this gene (NAT2). [provided by RefSeq, Sep 2019] | 8 | 18386301 | 18401218 | Human | 302 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1318865 | THUMPD1 | THUMP domain 1 NAT10 acetyltransferase adaptor | Enables RNA binding activity. Predicted to be involved in tRNA modification. Predicted to be located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 16 | 20733664 | 20741818 | Human | 98 | name | gene, protein-coding, VALIDATED [RefSeq] |
| 16552013 | NAA50P2 | NAA50 pseudogene 2 | | | | | Human | | old_gene_name | gene, unprocessed_pseudogene |
