| 1601800 | METTL2A | methyltransferase 2A, tRNA N3-cytidine | Enables tRNA (cytidine-3-)-methyltransferase activity. Involved in tRNA methylation. Located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 17 | 62423897 | 62453385 | Human | 53 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1350099 | METTL2B | methyltransferase 2B, tRNA N3-cytidine | This gene is a member of a family of methyltransferases that share homology with, but are distinct from, the UbiE family of methyltransferases. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provid ed by RefSeq, Jul 2008] | 7 | 128476748 | 128506602 | Human | 31 | symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1601964 | METTL22 | methyltransferase 22, Kin17 lysine | This gene encodes a member of the non-histone lysine methyltransferases. It interacts with its substrate, Kin17, which is involved in DNA repair and replication and mRNA processing. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] | 16 | 8621698 | 8667274 | Human | 74 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 2298732 | METTL23 | methyltransferase 23, arginine | The protein encoded by this gene functions as a transcription factor regulator in the transcriptional pathway for human cognition. It is a partner of the alpha subunit of the GA-binding protein transcription factor. Mutations in this gene cause mild autosomal recessive intellectual disability. Alter native splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014] | 17 | 76726041 | 76733881 | Human | 121 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1343913 | METTL24 | methyltransferase like 24 | Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025] | 6 | 110243940 | 110358349 | Human | 28 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1602087 | METTL25 | methyltransferase like 25 | Predicted to enable methyltransferase activity. Predicted to be involved in methylation. [provided by Alliance of Genome Resources, Jul 2025] | 12 | 82358529 | 82479239 | Human | 29 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1603944 | METTL26 | methyltransferase like 26 | INTERACTS WITH acrylamide; aristolochic acid A; arsenite(3-) | 16 | 634430 | 636305 | Human | 43 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1352777 | METTL27 | methyltransferase like 27 | This gene encodes a protein belonging to ubiE/COQ5 methyltransferase family. The gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.22-q11.23. [provided by RefSeq, Jul 2008] | 7 | 73834590 | 73842516 | Human | 246 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1602980 | METTL21A | methyltransferase 21A, HSPA lysine | Enables ATPase binding activity; Hsp70 protein binding activity; and protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025] | 2 | 207580635 | 207626053 | Human | 84 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1606433 | METTL21C | methyltransferase 21C, AARS1 lysine | Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Located in cytoplasm and nucleus. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025] | 13 | 102685747 | 102704300 | Human | 38 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1603041 | METTL25B | methyltransferase like 25B | Predicted to enable rRNA (adenine-N6,N6-)-dimethyltransferase activity. Predicted to be involved in rRNA methylation. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Jul 2025] | 1 | 156728469 | 156736960 | Human | 36 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 5490883 | METTL21EP | methyltransferase like 21E, pseudogene | Predicted to enable protein methyltransferase activity. Predicted to be involved in methylation. Predicted to be part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025] | 13 | 102880099 | 102896033 | Human | 17 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, PROVISIONAL [RefSeq] |
| 5132551 | METTL21AP1 | methyltransferase like 21A pseudogene 1 | | 21 | 39235328 | 39236050 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1602640 | ETFBKMT | electron transfer flavoprotein subunit beta lysine methyltransferase | Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase. Located in mitochondrial matrix. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025] | 12 | 31647160 | 31673114 | Human | 88 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1604024 | EEF1AKMT3 | EEF1A lysine methyltransferase 3 | Enables heat shock protein binding activity and protein-lysine N-methyltransferase activity. Involved in peptidyl-lysine methylation. Located in several cellular components, including centrosome; chromosome; and nucleoplasm. Part of protein-containing complex. [provided by Alliance of Genome Resourc es, Jul 2025] | 12 | 57772614 | 57782541 | Human | 57 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1314724 | VCPKMT | valosin containing protein lysine methyltransferase | Enables ATPase binding activity and protein-lysine N-methyltransferase activity. Involved in negative regulation of ATP-dependent activity and peptidyl-lysine trimethylation. Located in cytosol. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025] | 14 | 50102716 | 50116572 | Human | 70 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 16572359 | AL050350.1 | novel transcript, antisense to METTL24 | | | | | Human | | name | gene, lncrna |
| 16566740 | AC010655.4 | novel transcript, readthrough between HILPDA-METTL2B | | | | | Human | | name | gene, lncrna |