Mapk11 Gene Search Result

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2 records found for search term Mapk11

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1319634	MAPK11	mitogen-activated protein kinase 11	This gene encodes a member of a family of protein kinases that are involved in the integration of biochemical signals for a wide variety of cellular processes, including cell proliferation, differentiation, transcriptional regulation, and development. The encoded protein can be activated by proinfla ... (more) mmatory cytokines and environmental stresses through phosphorylation by mitogen activated protein kinase kinases (MKKs). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]	22	50263713	50270380	Human	228	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1354160	MAPKAPK5	MAPK activated protein kinase 5	The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11 ... (more) ht:700;'>MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]	12	111842228	111902222	Human	149	description	gene, protein-coding, REVIEWED [RefSeq]