Ilk Gene Search Result

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4 records found for search term Ilk

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
732855	ILK	integrin linked kinase	This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to ... (more) mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]	11	6603774	6610870	Human	287	symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
731849	ILKAP	ILK associated serine/threonine phosphatase	The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the ki ... (more) nase activity of ILK. Through the interaction with ILK, this protein may selectively affect the signaling process of ILK-mediated glycogen synthase kinase 3 beta (GSK3beta), and thus participate in Wnt signaling pathway. [provided by RefSeq, Jul 2008]	2	238170402	238203695	Human	62	symbol , COSMIC , name , description , Human Proteome Map , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1313204	LIMS2	LIM zinc finger domain containing 2	This gene encodes a member of a small family of focal adhesion proteins which interacts with ILK (integrin-linked kinase), a protein which effects protein-protein interactions with the extraceullar matrix. The encoded protein has five LIM domains, each domain fo ... (more) rming two zinc fingers, which permit interactions which regulate cell shape and migration. A pseudogene of this gene is located on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]	2	127638426	127681786	Human	159	old_gene_name , description	gene, protein-coding, REVIEWED [RefSeq]
1352322	PARVA	parvin alpha	This gene encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, mot ... (more) ility and survival. [provided by RefSeq, Dec 2010]	11	12376436	12535356	Human	156	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]