Ido1 Gene Search Result

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2 records found for search term Ido1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1346818	IDO1	indoleamine 2,3-dioxygenase 1	This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotoni ... (more) n. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]	8	39913891	39928790	Human	250	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
16560009	AC007991.3	novel transcript, antisense to IDO1 and IDO2					Human		name	gene, lncrna