| 737150 | HPX | hemopexin | This gene encodes a plasma glycoprotein that binds heme with high affinity. The encoded protein is an acute phase protein that transports heme from the plasma to the liver and may be involved in protecting cells from oxidative stress. [provided by RefSeq, Apr 2009] | 11 | 6431049 | 6440987 | Human | 206 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1606568 | LBX1 | ladybird homeobox 1 | This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles. [provided by Re fSeq, Jul 2008] | 10 | 101226994 | 101229463 | Human | 127 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1603306 | NKX1-1 | NK1 homeobox 1 | This gene encodes a transcription factor that belongs to NKX family of homeodomain-containing proteins which are critical regulators of organ development. In mice, the orthologous gene is expressed predominantly in the brainstem, in the vicinity of serotonergic neurons, and is required for the coord inated crosstalk of factors involved in the maintenance of energy homeostasis. Mice with a knockout of the orthologous gene lack subcutaneous fat and intra-abdominal epididymal and mesenteric white adipose tissue two weeks after birth, and die within three weeks after birth. [provided by RefSeq, Jul 2017] | 4 | 1402932 | 1406442 | Human | 20 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 1602108 | MSX2P1 | msh homeobox 2 pseudogene 1 | INTERACTS WITH aflatoxin B1; all-trans-retinoic acid; benzo[a]pyrene | 17 | 58156959 | 58159120 | Human | 11 | old_gene_symbol | gene, pseudo, PROVISIONAL [RefSeq] |
| 732278 | ECH1 | enoyl-CoA hydratase 1 | This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxi somal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. [provided by RefSeq, Jul 2008] | 19 | 38815422 | 38831794 | Human | 274 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1352191 | VENTXP7 | VENT homeobox pseudogene 7 | Homeobox genes encode DNA-binding proteins, many of which are thought to be involved in early embryonic development. Homeobox genes encode a DNA-binding domain of 60 to 63 amino acids referred to as the homeodomain. This pseudogene is a member of the Vent homeobox gene family. [provided by RefSeq, J ul 2008] | 3 | 21405726 | 21406708 | Human | 5 | old_gene_symbol | gene, pseudo, PROVISIONAL [RefSeq] |
| 1354153 | VENTX | VENT homeobox | This gene encodes a member of the Vent family of homeodomain proteins. The encoded protein may function as a transcriptional repressor and be involved in mesodermal patterning and hemopoietic stem cell maintenance. Multiple pseudogenes exist for this gene. A transcribed pseudogene located on chromos ome X may lead to antigen production in certain melanomas. [provided by RefSeq, Jul 2008] | 10 | 133237855 | 133241928 | Human | 64 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |