Esr1 Gene Search Result

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4 records found for search term Esr1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
736559	ESR1	estrogen receptor 1	This gene encodes an estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to t ... (more) he nucleus where it may form either a homodimer or a heterodimer with estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast cancer, endometrial cancer, and osteoporosis. This gene is reported to have dozens of transcript variants due to the use of alternate promoters and alternative splicing, however, the full-length nature of many of these variants remain uncertain. [provided by RefSeq, Jul 2020]	6	151656672	152129619	Human	2461	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
16572982	AL078582.2	novel transcript, antisense to ESR1					Human		name	gene, lncrna
16570450	AL078582.1	novel transcript, sense intronic to ESR1					Human		name	gene, lncrna
38642263	BNAT1	breast cancer associated ESR1 regulating natural antisense transcript 1		21	45403806	45406362	Human		name	gene, ncrna, VALIDATED [RefSeq]