| 1349633 | ELK1 | ETS transcription factor ELK1 | This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012] | X | 47635520 | 47650604 | Human | 290 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 733889 | KCNH4 | potassium voltage-gated channel subfamily H member 4 | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte tran sport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. The gene is brain-specific, and located in the neocortex and the striatum. It may be involved in cellular excitability of restricted neurons in the central nervous system. [provided by RefSeq, Jul 2008] | 17 | 42156891 | 42181142 | Human | 58 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1352658 | KCNH8 | potassium voltage-gated channel subfamily H member 8 | Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte tran sport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. [provided by RefSeq, Jul 2008] | 3 | 19148510 | 19535642 | Human | 70 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 4144514 | ELK1P1 | ELK1 pseudogene 1 | | 7 | 45391624 | 45392252 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1352536 | DEPP1 | DEPP autophagy regulator 1 | The expression of this gene is induced by fasting as well as by progesterone. The protein encoded by this gene contains a t-synaptosome-associated protein receptor (SNARE) coiled-coil homology domain and a peroxisomal targeting signal. Production of the encoded protein leads to phosphorylation and a ctivation of the transcription factor ELK1. [provided by RefSeq, Jul 2008] | 10 | 44976128 | 44978809 | Human | 196 | description | gene, protein-coding, REVIEWED [RefSeq] |
| 1605862 | SH3D19 | SH3 domain containing 19 | This gene encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. This protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 ;'>ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011] | 4 | 151120281 | 151325605 | Human | 110 | description | gene, protein-coding, REVIEWED [RefSeq] |