Dnmt3a Gene Search Result

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3 records found for search term Dnmt3a

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1606038	DNMT3A	DNA methyltransferase 3 alpha	CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in ... (more) de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]	2	25227874	25342590	Human	798	symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1351585	DNMT3AP1	DNA methyltransferase 3A pseudogene 1		2	66819925	66821517	Human		symbol , old_gene_name , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
1321014	SALL3	spalt like transcription factor 3	This gene encodes a sal-like C2H2-type zinc-finger protein, and belongs to a family of evolutionarily conserved genes found in species as diverse as Drosophila, C. elegans, and vertebrates. Mutations in some of these genes are associated with congenital disorders in human, suggesting their importanc ... (more) e in embryonic development. This protein binds to DNA methyltransferase 3 alpha (DNMT3A), and reduces DNMT3A-mediated CpG island methylation. It is suggested that silencing of this gene, resulting in acceleration of DNA methylation, may have a role in oncogenesis. [provided by RefSeq, Oct 2011]	18	78979818	78998969	Human	73	description	gene, protein-coding, VALIDATED [RefSeq]