Ddx3y Gene Search Result

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5 records found for search term Ddx3y

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1348882	DDX3Y	DEAD-box helicase 3 Y-linked	The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular inter ... (more) actions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]	Y	12903999	12920478	Human	126	symbol , old_gene_name , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
5133406	DDX3P1	DEAD-box helicase 3 pseudogene 1		X	74121043	74139454	Human		old_gene_symbol	gene, pseudo, INFERRED [RefSeq]
6480925	DDX3P2	DEAD-box helicase 3 pseudogene 2		X	74133004	74133114	Human		old_gene_symbol	gene, pseudo, INFERRED [RefSeq]
5133408	DDX3P3	DEAD-box helicase 3 pseudogene 3		4	103572002	103576529	Human		old_gene_symbol	gene, pseudo, INFERRED [RefSeq]
1352934	DDX3X	DEAD-box helicase 3 X-linked	The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, an ... (more) d unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]	X	41333308	41364472	Human	518	description	gene, protein-coding, REVIEWED [RefSeq]