Dbi Gene Search Result

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13 records found for search term Dbi

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
736302	DBI	diazepam binding inhibitor, acyl-CoA binding protein	This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein ... (more) is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]	2	119366977	119372543	Human	242	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
737564	TSPO	translocator protein	Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation ... (more) of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012]	22	43151559	43163242	Human	328	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1319842	INTS6	integrator complex subunit 6	DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addi ... (more) tion, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2015]	13	51334405	51453036	Human	117	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1347265	DBIP1	DBI pseudogene 1		6	79436667	79437228	Human		symbol , COSMIC , name , Human Proteome Map , old_gene_symbol	gene, pseudo, INFERRED [RefSeq]
1350044	DBIP2	DBI pseudogene 2		5	80603162	80603631	Human		symbol , COSMIC , name , Human Proteome Map , old_gene_symbol	gene, pseudo, INFERRED [RefSeq]
4145469	DBIP3	DBI pseudogene 3		16	4130592	4130995	Human		symbol , GTEx , COSMIC , name , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
16563574	AC009171.1	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI) pseudogene					Human		name	gene, processed_pseudogene
16560714	AC040926.1	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) (DBI) pseudogene					Human		name	gene, processed_pseudogene
1607074	ECI2	enoyl-CoA delta isomerase 2	This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, an ... (more) d polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011]	6	4115706	4135575	Human	177	old_gene_name	gene, protein-coding, VALIDATED [RefSeq]
4889641	DBIL5P	diazepam binding inhibitor-like 5, pseudogene	INTERACTS WITH 8-Br-cAMP; aristolochic acid A; butanal	17	752333	755336	Human	30	symbol , COSMIC , Human Proteome Map	gene, pseudo, VALIDATED [RefSeq]
4889622	DBIL5P2	diazepam binding inhibitor-like 5 pseudogene 2	INTERACTS WITH antirheumatic drug; bisphenol A; perfluorohexanesulfonic acid	2	63117851	63119542	Human	7	symbol , COSMIC , Human Proteome Map	gene, pseudo, VALIDATED [RefSeq]
1601703	ZNF326	zinc finger protein 326	Enables RNA polymerase II complex binding activity. Involved in regulation of DNA-templated transcription elongation and regulation of RNA splicing. Located in nucleoplasm. Part of DBIRD complex. [provided by Alliance of Genome Resources, Jul 2025]	1	89995110	90035533	Human	83	old_gene_name , description	gene, protein-coding, VALIDATED [RefSeq]
1605357	CCAR2	cell cycle and apoptosis regulator 2	Enables RNA polymerase II complex binding activity and enzyme inhibitor activity. Involved in several processes, including mitochondrial fragmentation involved in apoptotic process; regulation of primary metabolic process; and regulation of signal transduction. Located in several cellular components ... (more) , including mitochondrial matrix; nucleoplasm; and spindle. Part of DBIRD complex. [provided by Alliance of Genome Resources, Jul 2025]	8	22604757	22621514	Human	108	old_gene_name , description	gene, protein-coding, VALIDATED [RefSeq]