Cebpa Gene Search Result

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3 records found for search term Cebpa

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
69121	CEBPA	CCAAT enhancer binding protein alpha	This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of t ... (more) his protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013]	19	33299934	33302534	Human	1690	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
2303684	CEBPA-DT	CEBPA divergent transcript	ASSOCIATED WITH Colorectal Neoplasms; INTERACTS WITH aflatoxin B1; aristolochic acid A; arsane	19	33302821	33305057	Human	18	symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol	gene, ncrna, VALIDATED [RefSeq]
735345	PRKCH	protein kinase C eta	Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC f ... (more) amily members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. Mutations in this gene are associated with susceptibility to cerebral infarction. [provided by RefSeq, Sep 2015]	14	61187468	61550976	Human	219	description	gene, protein-coding, REVIEWED [RefSeq]