Amot Gene Search Result

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3 records found for search term Amot

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1344662	AMOT	angiomotin	This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate th ... (more) e inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]	X	112774877	112840831	Human	176	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1313196	AMOTL1	angiomotin like 1	The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that ... (more) regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]	11	94706460	94876748	Human	112	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
737053	AMOTL2	angiomotin like 2	Angiomotin is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a membe ... (more) r of the motin protein family. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]	3	134355345	134375417	Human	154	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]