| 1307298 | Zic4 | Zic family zinc finger 4 | ENCODES a protein that exhibits DNA binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH Dandy -Walker syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil | 8 | 100795860 | 100816276 | Rat | 73 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1316409 | ZIC4 | Zic family zinc finger 4 | This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. This gene is closely linked to the gene encoding zinc finger protein of th e cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Dec 2009] | 3 | 147386046 | 147406543 | Human | 69 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1316410 | Zic4 | zinc finger protein of the cerebellum 4 | Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in central nervous system development and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous sys tem; embryo mesenchyme; future brain; genitourinary system; and retina. Used to study Dandy-Walker syndrome. Orthologous to human ZIC4 (Zic family member 4). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 91247636 | 91271404 | Mouse | 80 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8826682 | Zic4 | Zic family zinc finger 4 | ENCODES a protein that exhibits DNA binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); ASSOCIATED WITH Dandy-Walker syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND I N nucleus (ortholog) | NW_004955474 | 10021777 | 10056870 | Chinchilla | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11770123 | ZIC4 | Zic family zinc finger 4 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH Dandy-Walker syndrome (ortholog); hepatocel lular carcinoma (ortholog); FOUND IN nucleus (inferred) | 3 | 144411069 | 144437019 | Bonobo | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12311278 | ZIC4 | Zic family member 4 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); RNA polymerase II transcription regulatory region sequence-specific DNA binding (inferred); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH Dandy-Walker syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND IN nucleus (inferred) | 23 | 42509742 | 42527918 | Dog | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12713809 | Zic4 | Zic family zinc finger 4 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH Dandy-Walker syndrome (ortholog); hepatocel lular carcinoma (ortholog); FOUND IN nucleus (inferred) | NW_004936519 | 8007605 | 8025831 | Squirrel | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18913883 | Zic4 | Zic family zinc finger 4 | ENCODES a protein that exhibits sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH Dandy-Walker syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND IN nucleus (inferred) | | | | Naked Mole-Rat | 16 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625877401 | Zic4 | Zic family zinc finger 4 | ENCODES a protein that exhibits DNA binding (ortholog); RNA polymerase II transcription regulatory region sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); ASSOCIATED WITH Dandy-Walker syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND I N nucleus (ortholog) | | | | Black Rat | 6 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14272171 | ZIC4 | Zic family member 4 | ENCODES a protein that exhibits DNA binding (inferred); metal ion binding (inferred); RNA polymerase II transcription regulatory region sequence-specific DNA binding (inferred); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH Dandy-Walker syndrome (ortholog); hepatocellular carcinoma (ortholog); FOUND IN nucleus (inferred) | | | | Pig | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18397245 | ZIC4 | Zic family zinc finger 4 | ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription factor activity, RNA polymerase II-specific (inferred); metal ion binding (inferred); INVOLVED IN regulation of transcription by RNA polymerase II (inferred); ASSOCIATED WITH Dandy-Walker syndrome (ortholog); hepatocel lular carcinoma (ortholog); FOUND IN nucleus (inferred) | | | | Green Monkey | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155234364 | zic4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155252950 | zic4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155258730 | zic4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 6481419 | ZIC4-AS1 | ZIC4 antisense RNA 1 | | 3 | 147386862 | 147388906 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
