| 1309774 | Zcchc8 | zinc finger CCHC-type containing 8 | ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway (ortholog); mRNA 3'-end processing (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); aplastic anemia (ortholog); dyskeratosis congenita ( ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol | 12 | 38530037 | 38553595 | Rat | 86 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1320291 | ZCCHC8 | zinc finger CCHC-type containing 8 | This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain. [provided by RefSeq, Apr 2017] | 12 | 122471600 | 122500932 | Human | 102 | symbol , old_gene_name , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320292 | Zcchc8 | zinc finger, CCHC domain containing 8 | Predicted to enable RNA binding activity. Predicted to be involved in mRNA 3'-end processing. Predicted to be located in nuclear body. Predicted to be part of TRAMP complex and catalytic step 2 spliceosome. Is expressed in several structures, including blastocyst; early embryo; eye; secondary oocyte ; and trunk somite. Orthologous to human ZCCHC8 (zinc finger CCHC-type containing 8). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 123836365 | 123859107 | Mouse | 116 | symbol , old_gene_name , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8732646 | Zcchc8 | zinc finger CCHC-type containing 8 | ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway (ortholog); mRNA 3'-end processing (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); aplastic anemia (ortholog); dyskeratosis congenita ( ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | NW_004955482 | 6163990 | 6184967 | Chinchilla | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11703497 | ZCCHC8 | zinc finger CCHC-type containing 8 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway (inferred); mRNA 3'-end processing (inferred); ASSOCIATED WITH acute myeloid leukemia ( ortholog); aplastic anemia (ortholog); dyskeratosis congenita (ortholog); FOUND IN nucleolus (ortholog) | 12 | 120075830 | 120103820 | Bonobo | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12144132 | ZCCHC8 | zinc finger CCHC-type containing 8 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway (inferred); mRNA 3'-end processing (inferred); ASSOCIATED WITH acute myeloid leukemia ( ortholog); aplastic anemia (ortholog); dyskeratosis congenita (ortholog); FOUND IN nucleolus (ortholog) | 26 | 6895873 | 6927262 | Dog | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12646601 | Zcchc8 | zinc finger CCHC-type containing 8 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway (inferred); mRNA 3'-end processing (inferred); ASSOCIATED WITH acute myeloid leukemia ( ortholog); aplastic anemia (ortholog); dyskeratosis congenita (ortholog); FOUND IN nucleolus (ortholog) | NW_004936558 | 2058513 | 2085686 | Squirrel | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18910886 | Zcchc8 | zinc finger CCHC-type containing 8 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway (ortholog); mRNA 3'-end processing (ortholog); ASSOCIATED WITH acute myeloid leukemia ( ortholog); aplastic anemia (ortholog); dyskeratosis congenita (ortholog); FOUND IN nucleolus (ortholog); TRAMP complex (ortholog) | | | | Naked Mole-Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13959317 | ZCCHC8 | zinc finger CCHC-type containing 8 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway (inferred); mRNA 3'-end processing (inferred); ASSOCIATED WITH acute myeloid leukemia ( ortholog); aplastic anemia (ortholog); dyskeratosis congenita (ortholog); FOUND IN nucleolus (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 31 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18369420 | ZCCHC8 | zinc finger CCHC-type containing 8 | ENCODES a protein that exhibits metal ion binding (inferred); nucleic acid binding (inferred); RNA binding (inferred); INVOLVED IN co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway (inferred); mRNA 3'-end processing (inferred); ASSOCIATED WITH acute myeloid leukemia ( ortholog); aplastic anemia (ortholog); dyskeratosis congenita (ortholog); FOUND IN nucleolus (ortholog) | | | | Green Monkey | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625895020 | Zcchc8 | zinc finger CCHC-type containing 8 | ENCODES a protein that exhibits RNA binding (ortholog); INVOLVED IN co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway (ortholog); mRNA 3'-end processing (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); aplastic anemia (ortholog); dyskeratosis congenita ( ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nucleolus (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20865798 | ZCCHC8 | zinc finger CCHC-type containing 8 | | | | | Green Monkey | | symbol | gene, protein-coding |
| 155245834 | zcchc8 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155245833 | zcchc8.L | | | | | | African Clawed Frog | | symbol | gene, null |