| 1359726 | Yod1 | YOD1 deubiquitinase | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); K48-linked deubiquitinase activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); ERAD pathway (ortholog); macroautophagy (ortholog); PA RTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 13 | 44727319 | 44733933 | Rat | 122 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1550942 | Yod1 | YOD1 deubiquitinase | Predicted to enable K48-linked deubiquitinase activity; cysteine-type deubiquitinase activity; and ubiquitin protein ligase binding activity. Predicted to be involved in several processes, including ERAD pathway; negative regulation of retrograde protein transport, ER to cytosol; and protein deubiqu itination. Predicted to be located in cytoplasm. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and respiratory system. Orthologous to human YOD1 (YOD1 deubiquitinase). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 130645064 | 130652093 | Mouse | 155 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1604806 | YOD1 | YOD1 deubiquitinase | Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cy steine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. The protein encoded by this gene belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013] | 1 | 207043849 | 207053116 | Human | 120 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 11790370 | YOD1 | YOD1 deubiquitinase | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN endoplasmic reticulum unfolded protein response (inferred); ERAD pathway (inferred); macroautophagy (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred) | 1 | 182621404 | 182635619 | Bonobo | 39 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12247146 | YOD1 | YOD1 deubiquitinase | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN endoplasmic reticulum unfolded protein response (inferred); ERAD pathway (inferred); macroautophagy (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred) | 7 | 6185650 | 6194005 | Dog | 36 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 626151235 | Yod1 | YOD1 deubiquitinase | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); K48-linked deubiquitinase activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN endoplasmic reticulum unfolded protein response (ortholog); ERAD pathway (ortholog); macroautophagy (ortholog); FO UND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog) | | | | Black Rat | 23 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 39131525 | YOD1 | YOD1 deubiquitinase | | | | | Chinchilla | | symbol , name | gene, protein-coding |
| 155255667 | yod1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18910003 | Yod1 | YOD1 deubiquitinase | ENCODES a protein that exhibits K48-linked deubiquitinase activity (ortholog); ubiquitin protein ligase binding (ortholog); INVOLVED IN macroautophagy (ortholog); negative regulation of retrograde protein transport, ER to cytosol (ortholog); protein K11-linked deubiquitination (ortholog); FOUND IN n ucleoplasm (ortholog); plasma membrane (ortholog) | | | | Naked Mole-Rat | 36 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 18600044 | YOD1 | YOD1 deubiquitinase | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN endoplasmic reticulum unfolded protein response (inferred); ERAD pathway (inferred); macroautophagy (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred) | | | | Green Monkey | 38 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 14210629 | YOD1 | YOD1 deubiquitinase | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN endoplasmic reticulum unfolded protein response (inferred); ERAD pathway (inferred); macroautophagy (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 37 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155238325 | yod1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 12602114 | CUNH1orf116 | chromosome unknown C1orf116 homolog | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN endoplasmic reticulum unfolded protein response (inferred); ERAD pathway (inferred); macroautophagy (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred) | NW_004936557 | 5586969 | 5615159 | Squirrel | 38 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 9012979 | LOC102027268 | chromosome unknown open reading frame, human C1orf116 | FOUND IN cytoplasm (ortholog); cytosol (ortholog); plasma membrane (ortholog) | NW_004955406 | 42537925 | 42573168 | Chinchilla | 5 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |